Articles of Interest
Cell Banking
Published on: Thursday 18, August 2011Category: Article of Interest
Citation: "Recommendations for Cell Banks Used in GXP Assays, Preparation, Characterization, and Storage" Ana T.
Drying Cells
Published on: Thursday 18, August 2011Category: Article of Interest
Citation: Chakraborty N, Menze MA, Malsam J, Aksan A, Hand SC, et al. 2011 Cryopreservation of Spin-Dried Mammalian Cells. PLoS ONE 6(9): e24916.
Listing of protective agents
Published on: Thursday 18, August 2011Category: Article of Interest
A listing of chemicals that have been associated with preservation:
acetamide, agaroses, alginates, alanine albumin, ammonium acetate, butanediol, chondroitin sulfate, chloroform, choline, cyclohexanediols**, dextrnas*, diethylene glycol, dimethyl acetamide, dimethyl formamide, dimethyl sulfoxide*, erythritol, lethano
Freezing of Tissue Specimens
Published on: Thursday 18, August 2011Category: Article of Interest
Freezing of Tissue Specimens: bibliography for Tissue Freezing Techniques
Preservation of Biofluids
Published on: Thursday 18, August 2011Category: Article of Interest
Hubel A, Aksan A, Skubiz APN, Wendt C, Zhong X, "State of the art in preservaion of fluid biospecimens", Biopreservation&Biobanking, 9(3): 237-244, 2011.
Why it is important: The state of the art in preservation of plasma/serum, urine, saliva, cerebrospinal fluid are reviewed with emphasis on the variables that in
Preservation of Nucleic Acids
Published on: Thursday 18, August 2011Category: Article of Interest
Anchordoquy TJ and Molina MC, "Preservation of DNA", Cell Preservation Technology, 5(4): 180-188, 2007.
Why it is important: It reminds us that preservation of DNA is not a completely solved problem. Freezing can damage DNA strands and make the sample less useful for future genomic techniques. A good revie
Economic Impact of Cell Therapy
Published on: Thursday 18, August 2011Category: Article of Interest
Mason C, Brindley DA, Culme-Seymour EJ, Davie NL, "Cell therapy Industry: billion dollar global buisness with unlimited potential", Regen Med 6(3); 265-272, 2011.
Why it is important: It demonstrates the manner by which tissue engineering/regenerative medicine has been eclipsed by cell therapy and the very real econom
Biospecimen identifiers
Published on: Monday 28, March 2011Category: Article of Interest
Nietfield JJ, Sugarman J, Litton JE, "The Bio-PIN: a concept to improve biobanking," Nature Reviews Cancer, 11: 303-308, 2011.
Why it is important: The paper proposes the structures of a method of identifying biospecimens based on single nucleotide polymorphisms. Issues of identification of samples and tracking
Biomarker Stability fo MMP-7, TIMP-1, VEGF and VEGF-R2
Published on: Monday 28, March 2011Category: Article of Interest
Kisland K, Kerna I, Kumm J, Jonsson, H, Tamm A, "Impact of cryopreservation on serum concentration of metalloptoteinases (MMP)-7, TIMP-1, vascular endothelial growth factor (VEGF) and VEGF-R2 in Biobank samples," Clin Chem Lab Med 49 (2): 229-235, 2011.
Why it is important: Studies on the stability of these biomarkers
Spatial Distribution of the State of Water in Frozen Mammalian Cells
Published on: Tuesday 02, November 2010Category: Article of Interest
Doug J, Malsam J, Bischof JC, Hubel A, Aksan A, "Spacial distribution of the state of water in frozen mammalian cells, Biophys J, 99: 2453-2459, 2010.
The direct determination of the state of intracellular water, mearsurement of the intercellular concentration of a cryoprotectant agent (dimethylsulfoxide), and the dis
